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Chemical Structure : C381
CAS No.: 1629138-41-5
Catalog No.: PC-72935Not For Human Use, Lab Use Only.
C381 (SRI011381) is a first-in-class, CNS bioactive compound capable of restoring lysosomal function with prominent antiinflammatory and neuroprotective activities.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $318 | In stock | |
| 100 mg | $528 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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C381 (SRI011381) is a first-in-class, CNS bioactive compound capable of restoring lysosomal function with prominent antiinflammatory and neuroprotective activities.
C381 physically targets the lysosome, promotes lysosomal acidification, increases breakdown of lysosomal cargo, and improves lysosome resilience to damage.
C381 has the potential both as a therapeutic and as a research compound to better understand lysosomal contributions to disease progression.
C381 is an orally bioavailable and brain penetrant Smad activator found in phenotypic screen.
| M.Wt | 329.488 | |
| Formula | C20H31N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-benzyl-3-cyclohexyl-1-(piperidin-4-ylmethyl)urea |
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1. Ryan T Vest, et al. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2121609119.
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