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C7683

Chemical Structure : C7683

CAS No.: 2573775-59-2

C7683 (C 7683)

Catalog No.: PC-21555Not For Human Use, Lab Use Only.

C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.

    Physicochemical Properties

    M.Wt 537.63
    Formula C30H34F3N5O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(3-((1s,3R)-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl)phenyl)-6-(((S)-3-methylpiperidin-1-yl)methyl)-4-(trifluoromethyl)isoindolin-1-one

    References

    1. Serah W Kimani, et al. Commun Biol. 2023 Dec 16;6(1):1272.

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