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Chemical Structure : CA-074
CAS No.: 134448-10-5
Catalog No.: PC-21936Not For Human Use, Lab Use Only.
CA-074 is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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CA-074 is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM.
CA-074 displays 10,000-30,000 times greater inhibitory activity than cathepsin H and L.
CA-074 improves memory and reduces beta-amyloid in transgenic Alzheimer disease mice.
| M.Wt | 383.45 | |
| Formula | C18H29N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-1-((2S,3S)-3-Methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylic acid |
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1. Towatari T, et al. FEBS Lett. 1991 Mar 25;280(2):311-5.
2. Montaser M, et al. Biol Chem. 2002 Jul-Aug;383(7-8):1305-8.
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