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Chemical Structure : CA-074 methyl ester
CAS No.: 147859-80-1
Catalog No.: PC-42108Not For Human Use, Lab Use Only.
CA-074 methyl ester is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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CA-074 methyl ester is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM.
CA-074 methyl ester displays 10,000-30,000 times greater inhibitory activity than cathepsin H and L.
CA-074 methyl ester improves memory and reduces beta-amyloid in transgenic Alzheimer disease mice.
| M.Wt | 397.4659 | |
| Formula | C19H31N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 26.66 mg/mL (Need warming) |
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| Chemical Name/SMILES |
L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-, methyl ester |
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1. Towatari T, et al. FEBS Lett. 1991 Mar 25;280(2):311-5.
2. Hook VY, et al. J Biol Chem. 2008 Mar 21;283(12):7745-53.
3. Montaser M, et al. Biol Chem. 2002 Jul-Aug;383(7-8):1305-8.
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