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Chemical Structure : CAM4066
Catalog No.: PC-35184Not For Human Use, Lab Use Only.
CAM4066 (CAM-4066) is a potent and selective CK2alpha (CK2α) inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors.
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CAM4066 (CAM-4066) is a potent and selective CK2alpha (CK2α) inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors.
CAM4066 inhibits CK2 activity by exploiting a pocket located outside the ATP binding site (alphaD pocket).
| M.Wt | 479.961 | |
| Formula | C26H26ClN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Iegre J, et al. Chem Sci. 2018 Feb 20;9(11):3041-3049.
2. Brear P, et al. Chem Sci. 2016 Nov 1;7(11):6839-6845.
3. De Fusco C, et al. Bioorg Med Chem. 2017 Jul 1;25(13):3471-3482.
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