CAT335 | TREK-1 activator | Probechem Biochemicals

Chemical Structure : CAT335

CAT335 (CAT-335)

Catalog No.: PC-22741Not For Human Use, Lab Use Only.

CAT335 is a small molecule covalent K2P2.1 (TREK-1) channel activator, selectively and irreversibly activates K2P2.1(TREK-1) S131C variant (TREK-1CG∗), but not wild-type K2P2.1(TREK-1)

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Biological Activity

CAT335 is a small molecule covalent K2P2.1 (TREK-1) channel activator, selectively and irreversibly activates K2P2.1(TREK-1) S131C variant (TREK-1CG∗), but not wild-type K2P2.1(TREK-1)

Physicochemical Properties

M.Wt	375.21
Formula	C18H12Cl2N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,4-dichlorobenzyl)-4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamide

References

1. Deal PE, et al. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9.

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CAT335 (CAT-335)

Biological Activity

Physicochemical Properties

References

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