Catalog No.: PC-26262Not For Human Use, Lab Use Only.
CAY10444 (BML-241) is a selective S1P3 receptor antagonist, inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 with IC50 of 11.6 uM.
CAY10444 (BML-241) is a selective S1P3 receptor antagonist, inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 with IC50 of 11.6 uM. CAY10444 (5 µM) inhibits S1P-induced growth and migration of MH7A rheumatoid fibroblast-like synoviocyte cells. CAY10444 (BML-241) (5 uM) inhibits the localization and release of IL-1β and prostaglandin E2 (PGE2) in MH7A cells.
Physicochemical Properties
M.Wt
287.46
Formula
C15H29NO2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-Undecylthiazolidine-4-carboxylic acid
References
1. Tao R, et al. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1022-8.
2. Koide Y, et al. J Med Chem. 2002 Oct 10;45(21):4629-38.
