Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CC-8977
Catalog No.: PC-21443Not For Human Use, Lab Use Only.
CC-8977 is a hgihly potent, selective inhibitor of calcium/calmodulin-dependent kinase kinase II (CaMKK2) with binding IC50 of 7 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CC-8977 is a hgihly potent, selective inhibitor of calcium/calmodulin-dependent kinase kinase II (CaMKK2) with binding IC50 of 7 nM.
CC-8977 inhibits phosphorylation of AMPK in LKB1 null A427 cells with IC50 of 170 nM.
CC-8977 shows CaMKK1 binding IC50 of 26 nM.
CC-8977 displays high selectivity against a panel of 259 kinases.
| M.Wt | 362.43 | |
| Formula | C22H22N2O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Young Chen, et al. Journal of Medicinal Chemistry 2023.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
