Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-JNK-CC-90001
CC-90001

Chemical Structure : CC-90001

CAS No.: 1403859-14-2

CC-90001 (CC90001, BMS-986360)

Catalog No.: PC-27739Not For Human Use, Lab Use Only.

CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.

Packing Price Stock Quantity
5 mg $78 In stock
10 mg $118 In stock
25 mg $198 In stock
50 mg $298 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.

Physicochemical Properties

M.Wt 321.43
Formula C16H27N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(tert-Butylamino)-4-(((1R,3R,4R)-3-hydroxy-4-methylcyclohexyl)amino)pyrimidine-5-carboxamide

References

1. Nagy MA, et al. J Med Chem. 2021 Dec 23;64(24):18193-18208.

2. Popmihajlov Z, et al. BMJ Open Respir Res. 2022 Jan;9(1):e001060.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: