Chemical Structure : CC-90001
CAS No.: 1403859-14-2
Catalog No.: PC-27739Not For Human Use, Lab Use Only.
CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
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CC-90001 (BMS-986360) is a potent c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 11 nM and 31 nM for JNK1 and JNK2 respectively, inhibits cellular phosphorylation of the direct JNK substrate c-Jun (p-cJun) with IC50 of 0.48 uM.
| M.Wt | 321.43 | |
| Formula | C16H27N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(tert-Butylamino)-4-(((1R,3R,4R)-3-hydroxy-4-methylcyclohexyl)amino)pyrimidine-5-carboxamide |
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1. Nagy MA, et al. J Med Chem. 2021 Dec 23;64(24):18193-18208.
2. Popmihajlov Z, et al. BMJ Open Respir Res. 2022 Jan;9(1):e001060.

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