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CCCP

Chemical Structure : CCCP

CAS No.: 555-60-2

CCCP (Carbonyl cyanide 3-chlorophenyl-hydrazone)

Catalog No.: PC-22180Not For Human Use, Lab Use Only.

CCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

Physicochemical Properties

M.Wt 204.62
Formula C9H5ClN4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Carbonyl cyanide 3-chlorophenyl-hydrazone

References

1. Kwon D, et al. Biochem Biophys Res Commun. 2017 Aug 30. pii: S0006-291X(17)31704-7.

2. Sinha D, et al. Sci Rep. 2017 Mar 17;7:44419.

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