CCG 224061 |CAS:2055990-82-2 Probechem Biochemicals

Chemical Structure : CCG 224061

CCG 224061 (CCG224061;CCG-224061)

Catalog No.: PC-60587Not For Human Use, Lab Use Only.

A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.

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Biological Activity

CCG 224061 is a potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.
CCG 224061 displays >30-fold selectivity over GRK5, GRK1, PKA and ROCK1.

Physicochemical Properties

M.Wt	325.387
Formula	C19H20FN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(((3S,4R)-4-(4-fluorophenyl)piperidin-3-yl)methoxy)-1H-indazole

References

1. Bouley R, et al. Mol Pharmacol. 2017 Dec;92(6):707-717.

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CCG 224061 (CCG224061;CCG-224061)

Biological Activity

Physicochemical Properties

References

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