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CCG 224061

Chemical Structure : CCG 224061

CAS No.: 2055990-82-2

CCG 224061 (CCG224061;CCG-224061)

Catalog No.: PC-60587Not For Human Use, Lab Use Only.

A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CCG 224061 is a potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 66 nM.
    CCG 224061 displays >30-fold selectivity over GRK5, GRK1, PKA and ROCK1.

    Physicochemical Properties

    M.Wt 325.387
    Formula C19H20FN3O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(((3S,4R)-4-(4-fluorophenyl)piperidin-3-yl)methoxy)-1H-indazole

    References

    1. Bouley R, et al. Mol Pharmacol. 2017 Dec;92(6):707-717.

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