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CCG 258001

Chemical Structure : CCG 258001

CAS No.: 2055990-96-8

CCG 258001 (CCG258001;CCG-258001)

Catalog No.: PC-60588Not For Human Use, Lab Use Only.

A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 280 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 280 nM; displays >100-fold selectivity over GRK5, GRK1, PKA and ROCK1.

Physicochemical Properties

M.Wt 339.414
Formula C20H22FN3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methoxy)-1H-indazole

References

1. Bouley R, et al. Mol Pharmacol. 2017 Dec;92(6):707-717.

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