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CCG 258001

Chemical Structure : CCG 258001

CAS No.: 2055990-96-8

CCG 258001 (CCG258001;CCG-258001)

Catalog No.: PC-60588Not For Human Use, Lab Use Only.

CCG 258001 is a potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 280 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CCG 258001 is a potent, relatively selective G protein-coupled receptor kinase GRK2 inhibitor with IC50 of 280 nM.
    CCG 258001 displays >100-fold selectivity over GRK5, GRK1, PKA and ROCK1.

    Physicochemical Properties

    M.Wt 339.414
    Formula C20H22FN3O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(((3S,4R)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methoxy)-1H-indazole

    References

    1. Bouley R, et al. Mol Pharmacol. 2017 Dec;92(6):707-717.

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