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CE-326597

Chemical Structure : CE-326597

CAS No.: 870615-40-0

CE-326597 (CE326597)

Catalog No.: PC-70197Not For Human Use, Lab Use Only.

CE-326597 is a potent, selective agonist of the human and rat CCK1 receptor with Ki of 36 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CE-326597 is a potent, selective agonist of the human and rat CCK1 receptor with Ki of 36 nM.
    CE-326597 significantly reduces food intake with minimal systemic exposure in rodents.

    Physicochemical Properties

    M.Wt 594.719
    Formula C37H34N6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (-)-4,5-Dihydro-4-(1H-indol-3-ylmethyl)-N-(1-methylethyl)-5-oxo-1-phenyl-N-(phenylmethyl)-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine-6-acetamide

    References

    1. Desai AJ, et al. J Med Chem. 2015 Dec 24;58(24):9562-77.

    2. Elliott RL, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6797-801.

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