Chemical Structure : CFM-2
CAS No.:
178616-26-7
CFM-2
(CFM2)
Catalog No. : PC-43072Not For Human Use, Lab Use Only.
CFM-2 is a selective, non-competitive AMPA receptor antagonist.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4307201
Biological Activity
CFM-2 is a selective, non-competitive AMPA receptor antagonist; significantly protectes against seizures induced by pentylentetrazole or picrotoxin in epilepsy-prone rats and in pentylenetetrazole kindled rat.
Physicochemical Properties
M.Wt
311.3352
Formula
C17H17N3O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4H-2,3-Benzodiazepin-4-one, 1-(4-aminophenyl)-3,5-dihydro-7,8-dimethoxy-
References
1. De Sarro G, et al. Eur J Pharmacol. 1999 Mar 5;368(2-3):149-59.
2. Chimirri A, et al. J Med Chem. 1997 Apr 11;40(8):1258-69.
3. De Sarro G, et al. Eur J Pharmacol. 2002 Sep 6;451(1):55-61.
4. Parada-Turska J, et al. Eur J Pharmacol. 2006 Mar 27;535(1-3):95-7.
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