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Chemical Structure : CFM-2
CAS No.: 178616-26-7
Catalog No.: PC-43072Not For Human Use, Lab Use Only.
CFM-2 is a selective, non-competitive AMPA receptor antagonist.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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CFM-2 is a selective, non-competitive AMPA receptor antagonist; significantly protectes against seizures induced by pentylentetrazole or picrotoxin in epilepsy-prone rats and in pentylenetetrazole kindled rat.
CFM-2 antagonizes the long-term increase in sensitivity of the convulsant effects of GABA function inhibitors in pentylentetrazole-kindled animals.
| M.Wt | 311.3352 | |
| Formula | C17H17N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4H-2,3-Benzodiazepin-4-one, 1-(4-aminophenyl)-3,5-dihydro-7,8-dimethoxy- |
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1. De Sarro G, et al. Eur J Pharmacol. 1999 Mar 5;368(2-3):149-59.
2. Chimirri A, et al. J Med Chem. 1997 Apr 11;40(8):1258-69.
3. De Sarro G, et al. Eur J Pharmacol. 2002 Sep 6;451(1):55-61.
4. Parada-Turska J, et al. Eur J Pharmacol. 2006 Mar 27;535(1-3):95-7.
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