Chemical Structure : CFT8634
CAS No.:
2704617-96-7
CFT8634
(CFT-8634)
Catalog No. : PC-73316Not For Human Use, Lab Use Only.
CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 PROTAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7331601
Biological Activity
CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 PROTAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.
Physicochemical Properties
M.Wt
710.799
Formula
C37H45F3N6O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(3S)-3-[[4-[4-[(4S)-1-[[4-(1,6-Dihydro-1,4,5-trimethyl-6-oxo-3-pyridinyl)-2,6-dimethoxyphenyl]methyl]-3,3-difluoro-4-piperidinyl]-1-piperazinyl]-3-fluorophenyl]amino]-2,6-piperidinedione
References
1. Patent WO2021178920A1.
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