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CGP-78608 hydrochloride

Chemical Structure : CGP-78608 hydrochloride

CAS No.: 1135278-54-4

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CGP-78608 hydrochloride (CGP78608 hydrochloride)

Catalog No.: PC-26281Not For Human Use, Lab Use Only.

CGP 78608 hydrochloride is a highly potent and selective antagonist of GluN1/GluN3 NMDAR, antagonizes GluN1/GluN2 receptors, acts as an ultra-potent and powerful potentiator of GluN1/GluN3A receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CGP 78608 hydrochloride is a highly potent and selective antagonist of GluN1/GluN3 NMDAR, antagonizes GluN1/GluN2 receptors, acts as an ultra-potent and powerful potentiator of GluN1/GluN3A receptors.

Physicochemical Properties

M.Wt 414.58
Formula C11H14BrClN3O5P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-, hydrochlorid

References

1. Hilgier W, et al. Brain Res. 2004 Jul 23;1015(1-2):186-8.

2. Gabra BH, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):186-94.

3. Grand T, et al. Nat Commun. 2018 Nov 13;9(1):4769.

4. Auberson YP, et al. Bioorg. Med. Chem. Lett. 1999;9:249–254.

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