CGP57380 |CAS:522629-08-9 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-MNK-CGP57380

Chemical Structure : CGP57380

CAS No.: 522629-08-9

CGP57380 (CGP 57380;CGP-57380)

Catalog No.: PC-42633Not For Human Use, Lab Use Only.

CGP57380 is a cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$378	In stock
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CGP57380 is a cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM.
CGP57380 has no inhibitory activity on p38, JNK1, ERK1/2, etc.
CGP57380 inhibits phosphorylation of eIF4E in cellular assays with IC50 of 3 uM.

Physicochemical Properties

M.Wt	244.2278
Formula	C11H9FN6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 43 mg/mL
Chemical Name/SMILES	1H-Pyrazolo[3,4-d]pyrimidine-3,4-diamine, N3-(4-fluorophenyl)-

References

1. Knauf U, et al. Mol Cell Biol. 2001 Aug;21(16):5500-11.

2. Wen Q, et al. Oncotarget. 2016 May 10;7(19):27787-801.

3. Lim S, et al. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2298-307.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

CGP57380 (CGP 57380;CGP-57380)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.