CHF-6366 | MABA | Probechem Biochemicals

Chemical Structure : CHF-6366

Catalog No.: PC-49312Not For Human Use, Lab Use Only.

CHF-6366 is a novel potent muscarinic antagonist and β2 agonist (MABA) with pKi of 10.2 and 11.4, respectively.

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Biological Activity

CHF-6366 is a novel potent muscarinic antagonist and β2 agonist (MABA) with pKi of 10.2 and 11.4, respectively.

M.Wt	764.880
Formula	C42H48N6O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)butyl 1-methyl-5-((3-((S)-phenyl(((((R)-quinuclidin-3-yl)oxy)carbonyl)amino)methyl)phenoxy)methyl)-1H-pyrazole-3-carboxylate

1. Laura Carzaniga, et al. J Med Chem. 2022 Aug 11;65(15):10233-10250.