CHI3L1 inhibitor 1-7

Chemical Structure : CHI3L1 inhibitor 1-7

Catalog No.: PC-25397Not For Human Use, Lab Use Only.

CHI3L1 inhibitor 1-7 is potent CHI3L1 binder with KD of 7.4 uM, inhibits the interaction between CHI3L1 and galectin-3 with IC50 of 15.4 uM, reduces GBM spheroid viability and inhibits STAT3 activation.

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Biological Activity

Physicochemical Properties

M.Wt	357.43
Formula	C17H19N5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-cyclopentyl-5-methyl-1H-pyrazol-4-yl)-2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetamide

References

1. Longfei Zhang, et al. bioRxiv [Preprint]. 2025 Aug 27:2025.08.24.671973.

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