CHI3L1 inhibitor 9e

Chemical Structure : CHI3L1 inhibitor 9e

Catalog No.: PC-25373Not For Human Use, Lab Use Only.

CHI3L1 inhibitor 9e is a small molecule inhibitor of Chitinase 3-like 1 (CHI3L1) with SPR KD of 19.11 uM, inhibits CHI3L1-STAT3 axis and elicits a dose-dependent reduction in pSTAT3 in GBM spheroids.

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Biological Activity

CHI3L1 inhibitor 9e is a small molecule inhibitor of Chitinase 3-like 1 (CHI3L1) with SPR KD of 19.11 uM, inhibits CHI3L1-STAT3 axis and elicits a dose-dependent reduction in pSTAT3 in GBM spheroids.

Physicochemical Properties

M.Wt	277.75
Formula	C14H16ClN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl)-2,3-dihydro-1H-inden-2-amine

References

1. Kaur B, et al. bioRxiv [Preprint]. 2025 Aug 12:2025.08.09.669500.

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