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CHIKV inhibitor 26

Chemical Structure : CHIKV inhibitor 26

CAS No.: 2568903-91-1

CHIKV inhibitor 26

Catalog No.: PC-23568Not For Human Use, Lab Use Only.

CHIKV inhibitor 26 is a potent Chikungunya virus (CHIKV) inhibitor with viral titer reduction EC90 of 0.45 uM, inhibits alphavirus replication by blocking subgenomic viral RNA translation and structural protein synthesis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CHIKV inhibitor 26 is a potent Chikungunya virus (CHIKV) inhibitor with viral titer reduction EC90 of 0.45 uM, inhibits alphavirus replication by blocking subgenomic viral RNA translation and structural protein synthesis.

Physicochemical Properties

M.Wt 443.54
Formula C23H17N5OS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(3-((4-cyanophenyl)amino)phenyl)thiazol-2-yl)-2-(methylthio)nicotinamide

References

1. Garzan A, et al. J Med Chem. 2024 Dec 2. doi: 10.1021/acs.jmedchem.4c01073.

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