Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CIQ
CAS No.: 486427-17-2
Catalog No.: PC-45533Not For Human Use, Lab Use Only.
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $104 | In stock | |
| 25 mg | $200 | In stock |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors; enhances receptor responses two-fold with an EC50 of 3 uM by increasing channel opening frequency without altering mean open time or EC50 values for glutamate or glycine; reverses MK-801-induced impairment in prepulse inhibition and working memory in Y-maze test in mice.
| M.Wt | 467.9413 | |
| Formula | C26H26ClNO5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Methanone, (3-chlorophenyl)[3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]- |
|
1. Mullasseril P, et al. Nat Commun. 2010 Oct 5;1:90.
2. Suryavanshi PS, et al. Br J Pharmacol. 2014 Feb;171(3):799-809.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
