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CJ-13610

Chemical Structure : CJ-13610

CAS No.: 179420-17-8

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CJ-13610 (CJ13610)

Catalog No.: PC-62454Not For Human Use, Lab Use Only.

CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
    CJ-13610 demonstrates antihyperalgesic activity in inflammatory pain models including the acute carrageenan model and the chronic inflammatory model.

    Physicochemical Properties

    M.Wt 393.505
    Formula C22H23N3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

    References

    1. Fischer L, et al. Br J Pharmacol. 2004 Jul;142(5):861-8.

    2. Cortes-Burgos LA, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):59-67.

    3. von Knethen A, et al. Cell Signal. 2013 Dec;25(12):2762-8.

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