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CJ-13610

Chemical Structure : CJ-13610

CAS No.: 179420-17-8

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CJ-13610 (CJ13610)

Catalog No.: PC-62454Not For Human Use, Lab Use Only.

CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.

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10 mg $148 In stock
25 mg $258 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
CJ-13610 demonstrates antihyperalgesic activity in inflammatory pain models including the acute carrageenan model and the chronic inflammatory model.

Physicochemical Properties

M.Wt 393.505
Formula C22H23N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide

References

1. Fischer L, et al. Br J Pharmacol. 2004 Jul;142(5):861-8.

2. Cortes-Burgos LA, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):59-67.

3. von Knethen A, et al. Cell Signal. 2013 Dec;25(12):2762-8.

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