CK-548 | Arp2/3 inhibitor | Probechem Biochemicals

Chemical Structure : CK-548

CK-548 (CK-0993548, CK548)

Catalog No.: PC-23089Not For Human Use, Lab Use Only.

CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.

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Biological Activity

CK-548 (CK-0993548) is a small molecule Arp2/3 complex inhibitor with the IC50 of 11 uM, inhibits HIV-1 nuclear migration and infection, suppresses microtubule assembly both in vitro and in vivo.

Physicochemical Properties

M.Wt	384.67
Formula	C15H11BrClNO2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-Bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-4-thiazolidinone

References

1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

2. Yamagishi Y, et al. Biochem Biophys Res Commun. 2018 Feb 12;496(3):834-839.

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CK-548 (CK-0993548, CK548)

Biological Activity

Physicochemical Properties

References

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