Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Cytoskeleton/Cell Adhesion Molecules-Arp2/3 complex-CK-636
CK-636

Chemical Structure : CK-636

CAS No.: 442632-72-6

Add to Favorites

CK-636 (CK636, CK-0944636, CK0944636)

Catalog No.: PC-44784Not For Human Use, Lab Use Only.

CK-636 (CK-0944636) is a small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM).

Packing Price Stock Quantity
10 mg $58 In stock
25 mg $98 In stock
50 mg $148 In stock
100 mg $238 In stock
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CK-636 (CK-0944636) is a small molecule Arp2/3 complex inhibitor that inhibits actin polymerization stimulated by fission yeast Arp2/3 complex (SpArp2/3 complex, IC50 = 24 uM).
CK-636 inhibits formation of actin filament comet tails by Listeria and podosomes by monocytes.

Physicochemical Properties

M.Wt 284.376
Formula C16H16N2OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 49 mg/mL
Chemical Name/SMILES

2-Thiophenecarboxamide, N-[2-(2-methyl-1H-indol-3-yl)ethyl]-

References

1. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

2. Zhou K, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-9.

3. Weeks HP, et al. Anticancer Res. 2016 Mar;36(3):1135-42.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: