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CK-869

Chemical Structure : CK-869

CAS No.: 388592-44-7

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CK-869 (CK869, CK-0157869)

Catalog No.: PC-62459Not For Human Use, Lab Use Only.

CK-869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM).

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5 mg $58 In stock
10 mg $88 In stock
25 mg $148 In stock
50 mg $258 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CK-869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, inhibits actin polymerization (IC50=11 uM).
CK-869 does not inhibit budding or fission yeast Arp2/3 complexes.

Physicochemical Properties

M.Wt 394.283
Formula C17H16BrNO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone

References

1. Hetrick B, et al. Chem Biol. 2013 May 23;20(5):701-12.

2. Nolen BJ, et al. Nature. 2009 Aug 20;460(7258):1031-4.

3. Ilatovskaya DV, et al. Cell Tissue Res. 2013 Dec;354(3):783-92.

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