CK1-IN-3c |CAS:756805-89-7 Probechem Biochemicals

Chemical Structure : CK1-IN-3c

CK1-IN-3c

Catalog No.: PC-62834Not For Human Use, Lab Use Only.

CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.

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Biological Activity

CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.
CK1-IN-3c shows selectivity over CDK5/p25, GSK-3α/β, and DYRK1A.
CK1-IN-3c elicits selective cytotoxic activity against the PANC-1 cell line.

Physicochemical Properties

M.Wt	347.378
Formula	C19H17N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6,7-dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)quinazolin-4-amine

References

1. Karthikeyan C, et al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2663-2667.

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CK1-IN-3c

Biological Activity

Physicochemical Properties

References

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