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CK1-IN-3c

Chemical Structure : CK1-IN-3c

CAS No.: 756805-89-7

CK1-IN-3c

Catalog No.: PC-62834Not For Human Use, Lab Use Only.

CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.
    CK1-IN-3c shows selectivity over CDK5/p25, GSK-3α/β, and DYRK1A.
    CK1-IN-3c elicits selective cytotoxic activity against the PANC-1 cell line.

    Physicochemical Properties

    M.Wt 347.378
    Formula C19H17N5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6,7-dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)quinazolin-4-amine

    References

    1. Karthikeyan C, et al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2663-2667.

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