CK2-IN-1 |CAS:863598-09-8 Probechem Biochemicals

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Chemical Structure : CK2-IN-1

CAS No.: 863598-09-8

CK2-IN-1 (Casein Kinase II Inhibitor IV)

Catalog No.: PC-62346Not For Human Use, Lab Use Only.

CK2-IN-1 is a potent, competitive inhibitor of ATP binding to Casein kinase 2 (CK2) with IC50 of 9 nM, induces differentiation of epidermal progenitor cells to terminally differentiated keratinocytes with EC50 of 0.1 uM.

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Biological Activity

CK2-IN-1 is a potent, competitive inhibitor of ATP binding to Casein kinase 2 (CK2) with IC50 of 9 nM, induces differentiation of epidermal progenitor cells to terminally differentiated keratinocytes with EC50 of 0.1 uM.

Physicochemical Properties

M.Wt	429.48
Formula	C24H23N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(3-(2-((3,4,5-trimethoxyphenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)phenyl)propanenitrile

References

1. Hong J. et al. ACS Chem Biol. 2007 Mar 20;2(3):171-5.

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CK2-IN-1 (Casein Kinase II Inhibitor IV)

Biological Activity

Physicochemical Properties

References

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