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CK2A2 inhibitor 65

Chemical Structure : CK2A2 inhibitor 65

CAS No.:

CK2A2 inhibitor 65

Catalog No.: PC-24634Not For Human Use, Lab Use Only.

CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively.
CK2A2 inhibitor 65 shares dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) as a kinome off-target with SGC-CK2-1 and CX-4945.

Physicochemical Properties

M.Wt 373.16
Formula C16H9BrN2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-bromo-2-(5-hydroxy-6-methoxypyridin-2-yl)-4-oxo-4H-chromene-6-carbonitrile

References

1. James K Tucker, et al. Bioorg Med Chem. 2025 Apr 16:127:118196.

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