Catalog No.: PC-25510Not For Human Use, Lab Use Only.
TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.
TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.
TBB also inhibits MESH1 (Metazoan SpoT Homologue 1) with an IC50 value of 4.7 uM.
Physicochemical Properties
M.Wt
434.71
Formula
C6HBr4N3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4,5,6,7-tetrabromobenzotriazole
References
1. Sarno S, et al. FEBS Lett. 2001 May 4;496(1):44-8.
2. De Moliner E, et al. Eur J Biochem. 2003 Aug;270(15):3174-81.
3. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.
