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CK2 inhibitor TBB

Chemical Structure : CK2 inhibitor TBB

CAS No.: 17374-26-4

CK2 inhibitor TBB (4,5,6,7-tetrabromobenzotriazole)

Catalog No.: PC-25510Not For Human Use, Lab Use Only.

TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.

Physicochemical Properties

M.Wt 434.71
Formula C6HBr4N3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,5,6,7-tetrabromobenzotriazole

References

1. Sarno S, et al. FEBS Lett. 2001 May 4;496(1):44-8.

2. De Moliner E, et al. Eur J Biochem. 2003 Aug;270(15):3174-81.

3. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.

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