Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CM11
Catalog No.: PC-60127Not For Human Use, Lab Use Only.
A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation; induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines, in a highly isoform-selective fashion and without triggering a hypoxic response; a novel chemical probe for selective VHL knockdown.
| M.Wt | 1179.456 | |
| Formula | C58H82N8O14S2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Maniaci C, et al. Nat Commun. 2017 Oct 10;8(1):830.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
