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CMK

Chemical Structure : CMK

CAS No.: 821794-90-5

CMK (RSK2 inhibitor CMK)

Catalog No.: PC-45919Not For Human Use, Lab Use Only.

CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM).

Physicochemical Properties

M.Wt 358.8221
Formula C18H19ClN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-

References

1. Cohen MS, et al. Science. 2005 May 27;308(5726):1318-21.

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