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Chemical Structure : CMPDA
CAS No.: 380607-77-2
Catalog No.: PC-43077Not For Human Use, Lab Use Only.
CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.
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CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.
CMPDA binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.
| M.Wt | 376.5345 | |
| Formula | C16H28N2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI) |
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1. Weeks AM, et al. Neuropharmacology. 2014 Oct;85:57-66.
2. Timm DE, et al. Mol Pharmacol. 2011 Aug;80(2):267-80.
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