CMPDA

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Chemical Structure : CMPDA

CAS No.: 380607-77-2

Catalog No.: PC-43077Not For Human Use, Lab Use Only.

CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.
CMPDA binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

Physicochemical Properties

M.Wt	376.5345
Formula	C16H28N2O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI)

References

1. Weeks AM, et al. Neuropharmacology. 2014 Oct;85:57-66.

2. Timm DE, et al. Mol Pharmacol. 2011 Aug;80(2):267-80.

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CMPDA

Biological Activity

Physicochemical Properties

References

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