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CMPDA

Chemical Structure : CMPDA

CAS No.: 380607-77-2

CMPDA

Catalog No.: PC-43077Not For Human Use, Lab Use Only.

CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays; binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

Physicochemical Properties

M.Wt 376.5345
Formula C16H28N2O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI)

References

1. Weeks AM, et al. Neuropharmacology. 2014 Oct;85:57-66.

2. Timm DE, et al. Mol Pharmacol. 2011 Aug;80(2):267-80.

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