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CNQX

Chemical Structure : CNQX

CAS No.: 115066-14-3

CNQX (FG 9065)

Catalog No.: PC-61717Not For Human Use, Lab Use Only.

CNQX (FG 9065) is a potent AMPA/kainate receptor antagonist with IC50 of 0.3/1.5 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CNQX (FG 9065) is a potent AMPA/kainate receptor antagonist with IC50 of 0.3/1.5 uM, respectively.
CNQX also is an antagonist at glycine modulatory site on NMDA receptor complex.

Physicochemical Properties

M.Wt 232.16
Formula C9H4N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-6-quinoxalinecarbonitrile

References

1. Sheardown MJ, et al. Science. 1990 Feb 2;247(4942):571-4.

2. McBain CJ, et al. Neurosci Lett. 1988 Nov 11;93(2-3):341-5.

3. Long SK, et al. Br J Pharmacol. 1990 Aug;100(4):850-4.

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