Chemical Structure : CNV1014802
CAS No.: 934240-30-9
Catalog No.: PC-43215Not For Human Use, Lab Use Only.
CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine, BIIB074) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo.
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CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine, BIIB074) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo.
Pain
Phase 2 Clinical
M.Wt | 314.3541 | |
Formula | C18H19FN2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-Pyrrolidinecarboxamide, 5-[4-[(2-fluorophenyl)methoxy]phenyl]-, (2S,5R)- |
1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78.
3. Zakrzewska JM, et al. Lancet Neurol. 2017 Apr;16(4):291-300.
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