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CNV1014802 hydrochloride

Chemical Structure : CNV1014802 hydrochloride

CAS No.: 934240-31-0

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CNV1014802 hydrochloride (GSK-1014802 hydrochloride;CNV-1014802 hydrochloride;Raxatrigine hydrochloride;Vixotrigine)

Catalog No.: PC-43216Not For Human Use, Lab Use Only.

CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo..

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5 mg $98 In stock
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50 mg $428 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CNV1014802 (GSK-1014802, Raxatrigine, Vixotrigine) is a potent, selective Nav1.7 sodium channel blocker, shows analgesic effects and potential in the treatment of cognitive symptoms of schizophrenia in vivo.

Physicochemical Properties

M.Wt 350.815
Formula C18H20ClFN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL
Chemical Name/SMILES

2-Pyrrolidinecarboxamide, 5-[4-[(2-fluorophenyl)methoxy]phenyl]-, hydrochloride (1:1), (2S,5R)-

References

1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.

2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78.

3. Zakrzewska JM, et al. Lancet Neurol. 2017 Apr;16(4):291-300.

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