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Chemical Structure : CNX-774
CAS No.: 1202759-32-7
Catalog No.: PC-38625Not For Human Use, Lab Use Only.
CNX-774 (CNX774) is a potent, selective orally active, irreversible BTK inhibitor with IC50 of <1 nM, covalently targets Cys481 of BTK.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | $458 | In stock | |
| 250 mg | Get quote |
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CNX-774 (CNX774) is a potent, selective orally active, irreversible BTK inhibitor with IC50 of <1 nM, covalently targets Cys481 of BTK.
| M.Wt | 499.50 | |
| Formula | C26H22FN7O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide |
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1. Akinleye A, et al. J Hematol Oncol. 2013 Aug 19;6:59.
2. Smiljkovic D, et al. Allergy. 2017 Nov;72(11):1666-1676.
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