CP-20-I

Chemical Structure : CP-20-I

Catalog No.: PC-26394Not For Human Use, Lab Use Only.

CP-20-I is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 180 nM in group-I S. aureus transcriptional reporter assays.

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Biological Activity

CP-20-I is a specific small molecule inhibitor of quorum sensing receptor AgrC in Staphylococcus aureus with IC50 of 180 nM in group-I S. aureus transcriptional reporter assays.
CP-20-I could potentially target the AgrC sensor domain in both S. epidermidis and S. aureus (∼30–40% conserved across species).

Physicochemical Properties

M.Wt	510.37
Formula	C18H15IN4O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-iodophenyl)-2-(thiophene-3-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxamide

References

1. Polaske TJ, et al. J Am Chem Soc. 2026 Mar 11;148(9):9199-9204.

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CP-20-I

Biological Activity

Physicochemical Properties

References

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