Catalog No.: PC-60675Not For Human Use, Lab Use Only.
CP-346086 is a potent, orally active microsomal triglyceride transfer protein (MTP) inhibitor that inhibits both human and rodent MTP with IC50 of 2 nM.
CP-346086 is a potent, orally active microsomal triglyceride transfer protein (MTP) inhibitor that inhibits both human and rodent MTP with IC50 of 2 nM.
CP-346086 inhibits apolipoprotein B (apoB) and triglyceride secretion (IC50=2.6 nM) without affecting apoA-I secretion or lipid synthesis.
CP-346086 lowers total, VLDL, and LDL cholesterol and triglycerides in rats.
