Chemical Structure : CP-465022
CAS No.:
199655-36-2
CP-465022
(CP465022)
Catalog No. : PC-61727Not For Human Use, Lab Use Only.
CP-465022 is a potent, selective, noncompetitive AMPA receptor (AMPAR) antagonist with IC50 of 36 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6172701
Biological Activity
CP-465022 is a potent, selective, noncompetitive AMPA receptor (AMPAR ) antagonist with IC50 of 36 nM.
Physicochemical Properties
M.Wt
462.95
Formula
C26H24ClFN4O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-(2-Chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone
References
1. Menniti FS, et al. Mol Pharmacol. 2000 Dec;58(6):1310-7.
2. Welch WM, et al. Bioorg Med Chem Lett. 2001 Jan 22;11(2):177-81.
3. Lazzaro JT, et al. Neuropharmacology. 2002 Feb;42(2):143-53.
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