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CS3

Chemical Structure : CS3

CAS No.: 1207457-11-1

CS3 (cIAP inhibitor CS3)

Catalog No.: PC-62350Not For Human Use, Lab Use Only.

CS3 is a potent, selective cIAP1 and cIAP2 inhibitor with IC50 of 16 nM and 85 nM respectively, shows no significant activity against XIAP (IC50>34 uM)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CS3 is a potent, selective cIAP1 and cIAP2 inhibitor with IC50 of 16 nM and 85 nM respectively, shows no significant activity against XIAP (IC50>34 uM).

    Physicochemical Properties

    M.Wt 506.651
    Formula C28H38N6O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (2S,3S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-3-methyl-N-(2-(pyrimidin-2-yl)phenyl)pyrrolidine-2-carboxamide

    References

    1. Ndubaku C, et al. ACS Chem Biol. 2009 Jul 17;4(7):557-66.

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