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CST967

Chemical Structure : CST967

CAS No.:

CST967 (CST-967)

Catalog No.: PC-22884Not For Human Use, Lab Use Only.

CST967 is a potent selective USP7 PROTAC degrader with DC50 of 17 nM, Dmax of 84% in MM.1S cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CST967 is a potent selective USP7 PROTAC degrader with DC50 of 17 nM, Dmax of 84% in MM.1S cells.

Physicochemical Properties

M.Wt 927.07
Formula C51H58N8O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carbonyl)piperidin-4-yl)-N-(3-((4-hydroxy-1-((R)-3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)propanamide

References

1. Arunima Murgai, et al. Chem Commun (Camb). 2022 Aug 4;58(63):8858-8861.

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