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Chemical Structure : CTA095
Catalog No.: PC-35181Not For Human Use, Lab Use Only.
CTA095 (CTA-095) is a potent Etk (BMX) and Src dual inhibitor with IC50 of 60 and 120 nM, respectively, shows no significant inhibition on Btk and Yes at 10 uM.
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CTA095 (CTA-095) is a potent Etk (BMX) and Src dual inhibitor with IC50 of 60 and 120 nM, respectively, shows no significant inhibition on Btk and Yes at 10 uM.
CTA095 induces autophagy and apoptosis, as well as synergistic effects with autophagy modulators in prostate cancer cells.
CTA095 inhibits the phosphorylation of Etk, Src and the downstream signals Stat3 and Akt in prostate cancer cells.
CTA095nano inhibits PC3 xenograft tumor growth in vivo.
| M.Wt | 553.666 | |
| Formula | C35H31N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Guo W, et al. PLoS One. 2013 Aug 15;8(8):e70910.
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