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Chemical Structure : CTLA-4 inhibitor D11.3
Catalog No.: PC-21772Not For Human Use, Lab Use Only.
CTLA-4 inhibitor D11.3 is a small molecule inhibitor of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) with IC50 of 0.97 uM in AlphaLISA assays.
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CTLA-4 inhibitor D11.3 is a small molecule inhibitor of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) with IC50 of 0.97 uM in AlphaLISA assays.
CTLA-4 inhibitor D11.3 (5 mg/kg or 12.5 mg/kg) markedly reduced tumor growth without affecting the body weight in in established syngeneic mouse models expressing transgenic humanized CTLA-4 protein.
| M.Wt | 346.86 | |
| Formula | C22H19ClN2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Navid Sobhani, et al. BJC Rep. 2024:2:4. doi: 10.1038/s44276-023-00035-5.
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