CU7218 | 14-3-3 inhibitor | Probechem Biochemicals

Chemical Structure : CU7218

CAS No.: 34330-04-6

CU7218 (CU 7218, CU-7218)

Catalog No.: PC-72267Not For Human Use, Lab Use Only.

CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3.

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Biological Activity

CU7218 is a small-molecule inhibitor of 14-3-3 protein, inhibits the interaction between 9J10 and 14-3-3.
CU7218 displaces FOXO3a and other substrate proteins from 14-3-3 and reproduces the cellular phenotypes induced by 9J10 expression.

Physicochemical Properties

M.Wt	242.267
Formula	C8H6N2O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,2,3,4-Tetrahydro-5-methyl-4-oxo-2-thioxothieno[2,3-d]pyrimidine-6-carboxylic acid

References

1. Amy Emery, et al. Cell Chem Biol. 2021 Nov 18;28(11):1602-1615.e9.

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CU7218 (CU 7218, CU-7218)

Biological Activity

Physicochemical Properties

References

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