Catalog No.: PC-60754Not For Human Use, Lab Use Only.
CV-6209 is a highly potent, selective platelet activating factor (PAF) inhibitor with IC50 of 75 and 170 nM for aggregation inhibition of rabbit and human platelets induced by PAF.
CV-6209 is a highly potent, selective platelet activating factor (PAF) inhibitor with IC50 of 75 and 170 nM for aggregation inhibition of rabbit and human platelets induced by PAF.
CV-6209 shows little to no effects on the aggregation induced by arachidonic acid, ADP and collagen.
CV-6209 inhibited PAF-induced hypotension in rats (ED50=0.009 mg/kg i.v.) with no effect on the hypotension induced by arachidonic acid, histamine, bradykinin and isoproterenol.
