CVI-LM001

Chemical Structure : CVI-LM001

Catalog No.: PC-26864Not For Human Use, Lab Use Only.

CVI-LM001 is a fluorobenzenesulfonate derivative of corydaline acting by suppressing the expression of PCSK9 gene and by stabilizing LDL mRNA, increases the LDL receptor levels by both inhibiting PCSK9 transcription and preventing LDL receptor mRNA degradation.

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Biological Activity

Physicochemical Properties

M.Wt	450.55
Formula	C26H26O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(6aS,12aS)-3,9-dimethoxy-5,6,6a,7,12,12a-hexahydrotetraphen-8-yl benzenesulfonate

References

1. Ahamad S, et al. J Med Chem. 2022 Dec 8;65(23):15513-15539.

2. Ferri N, et al. Atheroscler Plus. 2024 Dec 12;59:25-31.

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CVI-LM001

Biological Activity

Physicochemical Properties

References

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