CX-5011 | CK2 inhibitor | Probechem Biochemicals

Chemical Structure : CX-5011

CX-5011 (CX5011)

Catalog No.: PC-22790Not For Human Use, Lab Use Only.

CX-5011 is a potent, selective inhibitor of protein kinase CK2 with IC50 of <10 nM, induces cell death by apoptosis and acts synergistically with imatinib or the MEK-inhibitor U0126 in imatinib-resistant CML cells.

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Biological Activity

Physicochemical Properties

M.Wt	362.32
Formula	C20H11N4NaO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate

References

1. Anderes K, et al. Biochemistry. 2011 Oct 4;50(39):8478-88.

2. Salizzato V, et al. Oncotarget. 2016 Apr 5;7(14):18204-18.

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CX-5011 (CX5011)

Biological Activity

Physicochemical Properties

References

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