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CX546

Chemical Structure : CX546

CAS No.: 215923-54-9

CX546 (CX-546)

Catalog No.: PC-43074Not For Human Use, Lab Use Only.

CX546 is an AMPA receptor potentiator and GluR activator, binds specifically to the agonist bound non-desensitized receptor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CX546 is an AMPA receptor potentiator and GluR activator, binds specifically to the agonist bound non-desensitized receptor.
CX546 enhances cognitive function in rats, demonstrates neuroprotective in mice undergoing repeat ketamine anesthesia.

Physicochemical Properties

M.Wt 247.2897
Formula C14H17NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methanone, (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-

References

1. Nagarajan N, et al. Neuropharmacology. 2001 Nov;41(6):650-63.

2. Lauterborn JC, et al. J Neurosci. 2000 Jan 1;20(1):8-21.

3. Bahr BA, et al. Exp Neurol. 2002 Mar;174(1):37-47.

4. Leever JD, et al. Mol Pharmacol. 2003 Jul;64(1):5-10.

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