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CX614

Chemical Structure : CX614

CAS No.: 191744-13-5

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CX614 (CX-614)

Catalog No.: PC-61704Not For Human Use, Lab Use Only.

CX614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease.

Packing Price Stock Quantity
25 mg $88 In stock
50 mg $128 In stock
100 mg $188 In stock
250 mg $298 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CX614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease.
CX614 has also been shown to reduce the behavioural effects of methamphetamine in mice.

Physicochemical Properties

M.Wt 247.25
Formula C13H13NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one

References

1. Arai AC, et al. Mol Pharmacol. 2000 Oct;58(4):802-13.

2. Dicou E, et al. Brain Res. 2003 Apr 25;970(1-2):221-5.

3. Lauterborn JC, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):297-305.

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